包建春教授課題組在ACS APPLIED MATERIALS & INTERFACES發(fā)表研究論文
Conjugated Polymer-Quantum Dot Hybrid Materials for Pathogen Discrimination and Disinfection
Yuan, HT (Yuan, Haitao)[ 1,2 ] ; Zhao, H (Zhao, Hao)[ 2,3 ] ; Peng, K (Peng, Ke)[ 2,3 ] ; Qi, RL (Qi, Ruilian)[ 2 ] ; Bai, HT (Bai, Haotian)[ 2 ] ; Zhang, PB (Zhang, Pengbo)[ 2 ] ; Huang, YM (Huang, Yiming)[ 2 ]*; Lv, FT (Lv, Fengting)[ 2 ] ; Liu, LB (Liu, Libing)[ 2 ] ; Bao, JC (Bao, Jianchun)[ 1 ]*（包建春）; Wang, S (Wang, Shu)[ 2,3 ]*
[ 1 ]Nanjing Normal Univ, Sch Chem & Mat Sci, Nanjing 210023, Peoples R China
[ 2 ]Chinese Acad Sci, Inst Chem, Beijing Natl Lab Mol Sci, Key Lab Organ Solids, Beijing 100190, Peoples R China
[ 3 ]Univ Chinese Acad Sci, Coll Chem, Beijing 100049, Peoples R China
ACS APPLIED MATERIALS & INTERFACES，202005,12(19),21263-21269
In this work, a new platform for pathogen discrimination and killing based on a conjugated polymer-quantum dot hybrid material was designed and constructed through the fluorescence resonance energy transfer (FRET) process. The hybrid material comprises water-soluble anionic CdSe/ZnS quantum dots (QDs) and a cationic poly(fluorene-alt-phenylene) derivative (PFP) through electrostatic interactions, thus promoting efficient FRET between PFP and QDs. Upon addition of different pathogen strains, the FRET from PFP to QDs was interrupted because of the competitive binding between PFP and the pathogens. Complexation of PFP and QDs also reduced the dark toxicity to a more desirable level, therefore potentially realizing the controllable killing of pathogens. The technique provides a promising theranostic platform in pathogen discrimination and disinfection based on FRET and phototoxicity of the PFP and QDs.
文章鏈接：
https://pubs.acs.org/doi/10.1021/acsami.9b17783
版權(quán)與免責(zé)聲明：本網(wǎng)頁的內(nèi)容由收集互聯(lián)網(wǎng)上公開發(fā)布的信息整理獲得。目的在于傳遞信息及分享，并不意味著贊同其觀點或證實其真實性，也不構(gòu)成其他建議。僅提供交流平臺，不為其版權(quán)負(fù)責(zé)。如涉及侵權(quán)，請聯(lián)系我們及時修改或刪除。郵箱：sales@allpeptide.com