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論文表示，在小鼠胰腺beta-細胞內(nèi)特異性敲除Ig20/Madd基因可導(dǎo)致小鼠持續(xù)高血糖，該小鼠胰腺beta-細胞形態(tài)學(xué)及小鼠對胰島素的敏感性與野生型小鼠沒有明顯差異。正常小鼠胰島beta-細胞受葡萄糖刺激時可分泌胰島素，但Ig20/Madd基因敲除小鼠的胰腺beta-細胞受葡萄糖刺激時胰島素?zé)o法分泌到血液中發(fā)揮調(diào)控血糖的水平。

由于該項研究對揭示糖尿病的發(fā)病機理，以及開發(fā)因胰島素分泌不足所導(dǎo)致的糖尿病治療藥物具有重大意義，引起了廣泛而熱烈的關(guān)注。國內(nèi)外50多家媒體，包括教育部科技發(fā)展中心網(wǎng)站， UIC News, Science daily, Yahoo News,Medical Daily, Herald Scotland,Diabetes.co.uk, UK news等媒體均對此進行了報道。

《Diabetes》在線發(fā)表該文章的連接如下：

http://diabetes.diabetesjournals.org/content/early/2013/12/18/db13-0707.abstract

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1．國內(nèi)報道連接：

中國網(wǎng)站報道：

教育部科技發(fā)展中心網(wǎng)站報道

http://www.cutech.edu.cn/cn/gxkj/2014/01/1390154338006356.htm

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生物通網(wǎng)站報道

http://www.ebiotrade.com/newsf/2014-1/2014110110012144.htm

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分析測試百科網(wǎng)

http://wiki.antpedia.com/xiadahezuofaxianxingtangniaobingxiangguanjiyin-373648-news

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2．國外相關(guān)報道的連接：

UIC News: http://news.uic.edu/loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice

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Nature World News:??? http://www.natureworldnews.com/articles/5523/20140104/new-diabetes-treatment-take-inspiration-genetically-mutated-mice.htm

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Science Daily:???? http://www.sciencedaily.com/releases/2014/01/140103205137.htm

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Bio Portfolio:??? http://www.bioportfolio.com/news/article/1771059/Dysfunction-in-MADD-gene-in-mice-causes-fasting-hyperglycemia.html

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Medical Daily: http://www.medicaldaily.com/fixing-single-gene-may-reverse-adult-onset-diabetes-faulty-madd-gene-botches-insulin-delivery-266366

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South Asian Times: http://www.thesouthasiantimes.info/index.php?param=news/26901/Sci-Tech/42

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Vancouver Desi: http://www.vancouverdesi.com/lifestyle/breakthrough-for-type-2-diabetes-indian-origin-scientist/692781/

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Health Canal: http://www.healthcanal.com/metabolic-problems/diabetes/46304-loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice.html

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Silicon India News:?? http://www.siliconindia.com/news/usindians/IndianAmerican-Leads-New-Potential-Treatment-For-Diabetes-nid-158972-cid-49.html

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Pune Mirror:?? http://www.punemirror.in/article/26/20140106201401061024059899d466c79/Researchers-discover-a-potential-new-treatment-for-type-2-diabetes.html

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Herald Scotland:? http://www.heraldscotland.com/news/health/faulty-gene-linked-to-diabetes.23093178

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The Sentinel:? http://www.sentinelassam.com/international/story.php?sec=2&subsec=4&id=180089&dtP=2014-01-06&ppr=1

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The Morung Express:? http://www.morungexpress.com/frontpage/108967.html

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India.com: http://zeenews.india.com/news/health/health-news/indian-american-leads-new-potential-treatment-for-diabetes_25938.html

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Free Press Journal: http://freepressjournal.in/breakthrough-for-type-2-diabetes-indian-origin-scientist/

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Medical News Today: http://www.medicalnewstoday.com/articles/270816.php

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Fierce Biotech Research: http://www.fiercebiotechresearch.com/story/gene-defect-blocks-insulin-release-mice-may-cause-type-2-diabetes/2014-01-06

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dna India: http://www.dnaindia.com/health/report-dysfunction-in-single-gene-increases-risk-of-diabetes-1945114

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Emax Health: http://www.emaxhealth.com/1020/single-gene-isolated-could-mean-new-type-2-diabetes-treatment

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Deccan Chronicle: http://www.deccanchronicle.com/140104/lifestyle-health-and-well-being/article/dysfunction-single-gene-could-lead-diabetes

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The Siasat Daily: http://www.siasat.com/english/news/dysfunction-single-gene-could-lead-diabetes

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SILO breaker: http://news.silobreaker.com/indian-american-prof-finds-gene-linked-to-diabetes-in-mice-5_2267649693632692429

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Medical Daily: http://www.medicaldaily.com/fixing-single-gene-may-reverse-adult-onset-diabetes-faulty-madd-gene-botches-insulin-delivery-266366

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Top News.in: http://www.topnews.in/health/dysfunction-single-gene-could-lead-diabetes-218587

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LINK: http://thelinkpaper.ca/?p=35258

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Yahoo News: http://in.news.yahoo.com/dysfunction-single-gene-could-lead-diabetes-050416376.html

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Diabetes.co.uk: http://www.diabetes.co.uk/forum/threads/type-2s-are-you-madd.50929/

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Sarkaritel.com: http://www.sarkaritel.com/breakthrough-for-type-2-diabetes-indian-origin-scientist/

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Global Gujarat News: http://www.globalgujaratnews.in/article/breakthrough-for-type-2-diabetes-indian-origin-scientist/

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Pune Mirror: http://www.punemirror.in/article/26/20140106201401061024059899d466c79/Researchers-discover-a-potential-new-treatment-for-type-2-diabetes.html

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BioQuick News: http://www.bioquicknews.com/node/1504

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Telugu now: http://www.telugunow.com/health-tips/indian-american-leads-new-potential-treatment-diabetes.html

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Authint MAIL: http://www.authintmail.com/article/health/defective-madd-gene-responsible-type-2-diabetes-discovers-indian-origin-scientist

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The FREEPRESS journal: http://freepressjournal.in/dysfunction-in-gene-leads-to-diabetes/

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Bayou Buzz: http://www.bayoubuzz.com/healthcare/healthcare-news/item/574665-single-faulty-gene-causes-major-type-2-diabetes-symptom-in-mice

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ANI news: http://www.aninews.in/newsdetail9/story148530/dysfunction-in-single-gene-could-lead-to-diabetes.html

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UMMID.com: http://www.ummid.com/news/2014/January/05.01.2014/type-2-diabetese.html

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Healthloss.com: http://healthloss.com/health-journal-reduction-of-operate-of-a-single-gene-connected-to-diabetes-in-mice

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Biotechnology calendar, Inc: http://info.biotech-calendar.com/bid/103573/UCI-Bioresearchers-Present-Possible-Alternative-to-Insulin-Injections

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Igethair.com: http://www.igethair.com/2014/01/03/loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice/

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NewKerala.com: http://www.newkerala.com/news/story/108197/dysfunction-in-single-gene-could-lead-to-diabetes.html#.UtROFfvAaHc

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Bio-Medicine: http://news.bio-medicine.org/?q=medicine-news-1/loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice-124268

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PTInews: http://www.ptinews.com/news/4291235_Indo-American-leads-possible-treatment-for-diabetes-.html

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My Biologica: http://www.mybiologica.com/19854/health-en/loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice.html

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Haryana Headlines: http://www.haryanaheadlines.com/defective-madd-gene-responsible-for-type-2-diabetes-discovers-indian-origin-scientist/

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Newsr.in: http://newsr.in/n/Health/7509ajcfm/Dysfunction-in-single-gene-could-lead-to-diabetes.htm

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DiabetesHeadlines.com: http://en-maktoob.news.yahoo.com/breakthrough-type-2-diabetes-indian-origin-scientist-064610587.html

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Dailynews.com USA News: http://dailynewsen.com/2014/01/04/loss-of-function-of-a-single-gene-linked-to-diabetes-in-mice.html

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Counsel & Heal: http://www.counselheal.com/articles/8170/20140104/faulty-gene-tied-to-diabetes-in-mice.htm

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The Hawk: http://www.thehawkindia.com/dysfunction-single-gene-lead-diabetes

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Indiawest: http://www.indiawest.com/news/16068-indian-american-prof-finds-gene-linked-to-diabetes-in-mice.html

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MYSOOCHI.com: http://www.mysoochi.com/news/2014/01/05/breakthrough-for-type-2-diabetes-indian-origin-scientist/

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Livepunjab: http://www.livepunjab.com/content/20140107/researchers-identify-faulty-gene-linked-diabetes-animal-study-111464.html

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Truthdive: http://truthdive.com/2014/01/04/Dysfunction-in-single-gene-could-lead-to-diabetes.html

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Diet for India: http://www.diet-for-india.in/diabetes/dysfunction-in-single-gene-could-lead-to-diabetes-zee-news/

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Disability Today: http://www.disabilitytoday.co.uk/dysfunction-in-single-gene-increases-risk-of-diabetes-daily-news-analysis/

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Canal Diabetes: http://www.canaldiabetes.com/un-gen-defectuoso-causa-diabetes/

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UK news: http://www.newsrt.co.uk/news/faulty-gene-linked-to-diabetes-2160001.html

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Samachar.com: http://www.samachar.com/breakthrough-for-type-2-diabetes-indian-origin-scientist-obfoK3hbghi.html

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India TV: http://www.indiatvnews.com/news/world/indian-origin-scientist-in-us-claims-breakthrough-for-type-2-dia-15612.html

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Maha Media: http://www.mahamediaonline.com/newsDetails.jsp?Id=1908

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TopNews.in: http://www.topnews.in/health/dysfunction-single-gene-could-lead-diabetes-218587

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