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Z-DEVD-CMK reversibly inhibits caspase-3.
編號(hào):158243
CAS號(hào):250584-13-5
單字母:Z-DEVD-CMK
編號(hào): | 158243 |
中文名稱(chēng): | 四肽Cbz-DEVDCMK |
CAS號(hào): | 250584-13-5 |
單字母: | Z-DEVD-CMK |
三字母: | Cbz N端Cbz保護(hù) -Asp天冬氨酸 -Glu谷氨酸 -Val纈氨酸 -Asp天冬氨酸 -CMKC端氯甲基酮修飾 |
氨基酸個(gè)數(shù): | 4 |
分子式: | C27H35O13N4l1 |
平均分子量: | 623.59 |
精確分子量: | 623.22 |
等電點(diǎn)(PI): | - |
pH=7.0時(shí)的凈電荷數(shù): | -3 |
平均親水性: | 1.875 |
疏水性值: | -1.58 |
外觀與性狀: | 白色粉末狀固體 |
消光系數(shù): | - |
來(lái)源: | 人工化學(xué)合成,僅限科學(xué)研究使用,不得用于人體。 |
純度: | 95%、98% |
鹽體系: | 可選TFA、HAc、HCl或其它 |
儲(chǔ)存條件: | 負(fù)80℃至負(fù)20℃ |
標(biāo)簽: | CMK(氯甲基酮)修飾 CBZ修飾肽 |
Z-DEVD-CMK reversibly inhibits caspase-3.
DOI | 名稱(chēng) | |
---|---|---|
10.1038/sj.cdd.4401247 | Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity | 下載 |
10.1016/j.chembiol.2004.11.010 | Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover | 下載 |
10.1074/jbc.M408475200 | Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin | 下載 |
10.1152/ajpheart.00338.2008 | Activation of caspase-3 may not contribute to postresuscitation myocardial dysfunction | 下載 |
10.1038/cddis.2011.139 | Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells | 下載 |
10.1006/excr.1997.3928 | Multiple intracellular pathways interfere with the activation of a CPP32-like protease induced by serum deprivation of AKR-2B cells | 下載 |
10.1016/s0014-5793(98)00424-4 | Caspases disrupt mitochondrial membrane barrier function | 下載 |
10.1074/jbc.273.47.31245 | Tumor necrosis factor induces ceramide oscillations and negatively controls sphingolipid synthases by caspases in apoptotic Kym-1 cells | 下載 |
10.1016/s0167-4838(02)00333-3 | Probing the caspase-3 active site by fluorescence lifetime measurements | 下載 |
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10.1007/BF03033795 | Death and neuroprotection of retinal ganglion cells after different types of injury | 下載 |