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150113-99-8,四肽Decanoyl-Arg-Val-Lys-Arg-chloromethylketon,Decanoyl-Arg-Val-Lys-Arg-CMK,C10-RVKR-CMK,杭州專肽生物的產(chǎn)品

四肽Decanoyl-Arg-Val-Lys-Arg-chloromethylketon

Dec-RVKR-CMK binds to the catalytic site of furin and therefore acts as a potent inhibitor of cleavage and fusion activity of viral glycoproteins, as well as virus replication. Furthermore it was demonstrated that Dec-RVKR-CMK decreased the production of

編號：113563

CAS號：150113-99-8

單字母：Decanoicacid-RVKR-CMK

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  • 編號:113563
    中文名稱:四肽Decanoyl-Arg-Val-Lys-Arg-chloromethylketon
    英文名:Decanoyl-Arg-Val-Lys-Arg-chloromethylketon
    CAS號:150113-99-8
    單字母:Decanoicacid-RVKR-CMK
    三字母:Decanoicacid

    癸酸修飾、癸?；?/p>-Arg

    精氨酸

    -Val

    纈氨酸

    -Lys

    賴氨酸

    -Arg

    精氨酸

    -CMK

    C端氯甲基酮修飾

    氨基酸個數(shù):4
    分子式:C34H66O6N11l1
    平均分子量:724.96
    精確分子量:724.52
    等電點(PI):-
    pH=7.0時的凈電荷數(shù):3
    平均親水性:1.875
    疏水性值:-2.18
    外觀與性狀:白色粉末狀固體
    消光系數(shù):-
    來源:人工化學合成，僅限科學研究使用，不得用于人體。
    純度:95%、98%
    鹽體系:可選TFA、HAc、HCl
    儲存條件:負80℃至負20℃
    標簽:CMK(氯甲基酮)修飾   

  • Dec-RVKR-CMK binds to the catalytic site of furin and therefore acts as a potent inhibitor of cleavage and fusion activity of viral glycoproteins, as well as virus replication. Furthermore it was demonstrated that Dec-RVKR-CMK decreased the production of β-amyloid-induced active matrix metalloproteinase 2 in U87 cells. Apart from furin, Dec-RVKR-CMK also inhibited the proprotein convertases PC7/LPC, PACE4, and PC6 (W.Garten, personal communication).

  • DOI名稱
    10.1038/360358a0Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160下載
    10.1016/0042-6822(89)90103-7Inhibition of proteolytic activation of influenza virus hemagglutinin by specific peptidyl chloroalkyl ketones下載
  • 暫時沒有數(shù)據(jù)
  • 暫時沒有數(shù)據(jù)