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L-肌肽作為化妝品原料可以有效增白肌膚及防止肌膚衰老的作用,是一種天然抗氧化劑。
編號(hào):153380
CAS號(hào):305-84-0
單字母:H2N-βA-H-OH
編號(hào): | 153380 |
中文名稱: | 二肽L-肌肽,N-beta-丙氨酰-L-組氨酸 |
中文同義詞: | β-丙氨?;?L-組氨酸/N-β-丙氨酰-L-組氨酸/L-肉縮氨基酸/ 卡諾信 |
英文名: | L-Carnosine,N-beta-Alanyl-L-histidine |
CAS號(hào): | 305-84-0 |
單字母: | H2N-βA-H-OH |
三字母: | H2N N端氨基:N-terminal amino group。在肽或多肽鏈中含有游離a-氨基的氨基酸一端。在表示氨基酸序列時(shí),通常將N端放在肽鏈的左邊。 -βAlaβ丙氨酸 -HisL-組氨酸:histidine。系統(tǒng)命名為(2S)-氨基-3-(4-咪唑基)丙酸。其側(cè)鏈帶有弱堿性的咪唑基,為編碼氨基酸。是幼小哺乳動(dòng)物的必需氨基酸。符號(hào):H,His。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽鏈中含有游離羧基的氨基酸一端。在表示氨基酸序列時(shí),通常將C端放在肽鏈的右邊。 |
氨基酸個(gè)數(shù): | 2 |
分子式: | C9H14N4O3 |
平均分子量: | 226.23 |
精確分子量: | 226.11 |
等電點(diǎn)(PI): | - |
pH=7.0時(shí)的凈電荷數(shù): | 1.21 |
平均親水性: | -0.5 |
疏水性值: | -3.2 |
外觀與性狀: | 白色粉末 |
熔點(diǎn): | 253℃ |
消光系數(shù): | - |
來(lái)源: | 人工化學(xué)合成,僅限科學(xué)研究使用,不得用于人體。 |
純度: | ≥99% |
應(yīng)用: | 化妝品原料 |
儲(chǔ)存條件: | 負(fù)80℃至負(fù)20℃ |
標(biāo)簽: | 氨基酸衍生物肽 二肽(Dipeptide) |
Carnosine is a major component of the non-protein fraction of vertebrate skeletal muscle. It acts as an aldehyde scavenger, a likely lipofuscin (age pigment) precursor and possible modulator of diabetic complications, atherosclerosis and Alzheimer's disease. Janssen et al. showed that carnosine acts as a protective factor in diabetic nephropathy.
DOI | 名稱 | |
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10.1002/bio.644 | Thiols enhance the sensitivity of luminescent assays for non-cross-linked and covalently cross-linked aminophthalhydrazides | 下載 |
10.1126/sageke.2005.18.pe12 | Carnosine: a versatile antioxidant and antiglycating agent | 下載 |
10.2337/diabetes.54.8.2320 | Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1 | 下載 |
10.1016/j.lfs.2005.09.054 | Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and L-carnosine in ophthalmic and skin care products | 下載 |
10.1586/ern.09.32 | Carnosine, diabetes and Alzheimer's disease | 下載 |
10.1021/jf900948r | Sensory-directed identification of beta-alanyl dipeptides as contributors to the thick-sour and white-meaty orosensation induced by chicken broth | 下載 |
10.1021/jf100591c | Sensory-guided identification of N-(1-methyl-4-oxoimidazolidin-2-ylidene)-alpha-amino acids as contributors to the thick-sour and mouth-drying orosensation of stewed beef juice | 下載 |
10.1007/s12010-013-0330-z | Characterization of a (D)-stereoselective aminopeptidase (DamA) exhibiting aminolytic activity and halophilicity from Aspergillus oryzae | 下載 |