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專注多肽 服務(wù)科研
亮丙瑞林Ph.Eur的雜質(zhì)B。專著。
編號:200203
CAS號:112642-11-2
單字母:Pyr-hWSYlLRP-NHEt
編號: | 200203 |
中文名稱: | 八肽pGlu-DHis-WSY-DLeu-LRP-NHEt |
CAS號: | 112642-11-2 |
單字母: | Pyr-hWSYlLRP-NHEt |
三字母: | Pyr 焦谷氨酸 -DHisD型組氨酸 -TrpL-色氨酸:tryptophan[e]。系統(tǒng)命名為(2S)-氨基-3-(3-吲哚基)丙酸。是編碼氨基酸,哺乳動物的必需氨基酸。符號:W,Trp。某些抗菌素中含有 D-色氨酸。 -SerL-絲氨酸:serine。系統(tǒng)命名為(2S)-氨基-3-羥基丙酸。是編碼氨基酸。因可從蠶絲中獲得而得名。符號:S,Ser。在絲原蛋白及某些抗菌素中含有 D-絲氨酸。 -TyrL-酪氨酸:tyrosine。系統(tǒng)命名為(2S)-氨基-3-(4-羥基苯基)丙酸。是編碼氨基酸。符號:Y,Tyr。 -DLeuD型亮氨酸 -LeuL-亮氨酸:leucine。系統(tǒng)命名為(2S)-氨基-4-甲基戊酸。是編碼氨基酸。是哺乳動物的必需氨基酸。符號:L,Leu。 -ArgL-精氨酸:arginine。系統(tǒng)命名為(2S)-氨基-5-胍基戊酸。在生理條件下帶正電荷,為編碼氨基酸。是幼小哺乳動物的必需氨基酸。符號:R,Arg。 -ProL-脯氨酸:proline。系統(tǒng)命名為吡咯烷-(2S)-羧酸。為亞氨基酸。是編碼氨基酸。在肽鏈中有特殊作用,如易形成順式的肽鍵等。符號:P,Pro。 -NHEtC端乙胺基化修飾 |
氨基酸個數(shù): | 8 |
分子式: | C59H84N16O12 |
平均分子量: | 1209.4 |
精確分子量: | 1208.65 |
等電點(PI): | - |
pH=7.0時的凈電荷數(shù): | 2.24 |
平均親水性: | -1.0857142857143 |
疏水性值: | -0.54 |
消光系數(shù): | 6990 |
來源: | 人工化學合成,僅限科學研究使用,不得用于人體。 |
儲存條件: | 負80℃至負20℃ |
標簽: | D型氨基酸肽 |
Impurity B of the Leuprorelin Ph. Eur. monograph.
很多蛋白在細胞中非常容易被降解,或被標記,進而被選擇性地破壞。但含有部分D型氨基酸的多肽則顯示了很強的抵抗蛋白酶降解能力。
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