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634911-78-7,五肽Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethyl,Cbz-Asp(OMe)-Glu(OMe)-Val-DLeu-Asp(OMe)-FMK,Z-D(OMe)-E(OMe)-V-DLeu-D(OMe)-FMK,杭州專肽生物的產品

五肽Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethyl

Z-DEVD-FMK 的甲酯，一種特定的 caspase-3 抑制劑。Z-D(OMe)E(OMe)VD(OMe)-FMK 降低了紅藻氨酸誘發(fā)的癲癇持續(xù)狀態(tài) (SE) 后發(fā)生的神經元死亡的脆弱性。

編號：200420

CAS號：634911-78-7

單字母：Z-D(OMe)-E(OMe)-Vl-D(OMe)-FMK

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  • 編號:200420
    中文名稱:五肽Z-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethyl
    CAS號:634911-78-7
    單字母:Z-D(OMe)-E(OMe)-Vl-D(OMe)-FMK
    三字母:Cbz

    N端Cbz保護

    -Asp(OMe)

    暫無說明

    -Glu(OMe)

    暫無說明

    -Val

    纈氨酸

    -DLeu

    D型亮氨酸

    -Asp(OMe)

    暫無說明

    -FMK

    C端氟甲基酮修飾

    氨基酸個數:5
    分子式:C36H52O13N5F1
    平均分子量:781.82
    精確分子量:781.35
    等電點(PI):-
    pH=7.0時的凈電荷數:-
    平均親水性:-1.65
    疏水性值:4
    消光系數:-
    來源:人工化學合成，僅限科學研究使用，不得用于人體。
    儲存條件:負80℃至負20℃
    標簽:D型氨基酸肽    CBZ修飾肽    側鏈保護基肽    FMK修飾肽   

  • Methyl ester of Z-DEVD-FMK, a specific caspase-3 inhibitor. Z-D(OMe)E(OMe)VD(OMe)-FMK reduces vulnerability to the neuronal death that occurs in the aftermath of kainic acid-evoked status epilepticus (SE).

    很多蛋白在細胞中非常容易被降解，或被標記，進而被選擇性地破壞。但含有部分D型氨基酸的多肽則顯示了很強的抵抗蛋白酶降解能力。

  • DOI名稱
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